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UPLC and LCMS Applications

Based upon recent development of UPLC/UHPLC, UPLC-MS, LC-MS techniques, specially combined applications with high sensitive detectors, such as Mass, PDA, ELSD, CAD, etc., ultra low limits and efficient molecular structure of proteins, peptides, oligonucleotides and other chemicals are applied in bio-engineering and pharmaceutics.

These instruments have two key components: the ion source, which generates the ions, and the mass analyzer, which sorts the ions. Much of the advancement in LC/MS over the last decade has been in the development of ion sources and techniques that ionize the analyte molecules and separate the resulting ions from the mobile phase.

When ionization occurs in the presence of alkali metal, some components are susceptible to form adducts or clusters that may mask the true molecular MH+ ions.

Anaqua LC/MS solvents are manufactured specifically to meet the needs of modern UPLC, UPLC/MS and LC/MS instruments, checked and guaranteed to contain low levels of contaminants and ionic background. Specific UV tests and gradient elution control are also guaranteed to ensure reproducibility for such high resolution and high sensitive analysis. Anaqua is one of suppliers of such grade solvents, acids and salts in the world.

Kit of UPLC grade solvents and reagents is available.

Such grade chemicals are applied for UPLC, UHPLC, MPLC, UPLC-Mass, LC-MS, LC-MS-MS, HPLC, HPLC-Gradient, etc. with features of ultra-high purity, ultra-low impurity peaks during gradient applications, excellent far UV scan, ultra low ion background, packed under nitrogen and submicron ultra fine filtration.